Intertek ASG Laboratory, Manchester, UK

Pharmaceutical Trace Metal Analysis

Trace metals detection, identification and quantification in sample matrices

Intertek ASG provides a full range of trace analysis testing solutions for clients requiring identification and quantification of trace metals content in a diverse range of organic materials and samples. Quantitative and semi quantitative analysis are available to ppm (parts per million), ppb (parts per billion) and ppt (parts per trillion) detection levels depending upon the sample and technique used. Rapid sample screening to detailed high resolution for detection and measurement of trace metals content is readily available. Instrumentation is qualified to GLP and GMP/cGMP standards. A wider range of technologies is also available from the global Intertek laboratory network.

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Email ASG for more information   asg.nwtc@intertek.com

Telephone ASG for more information  +44 (0) 161 721 5247

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Pharamceutical Trace Metal Analysis - Trace metals detection, identification and quantification in sample matrices

 

  

Trace metal analysis capabilities:

  • Raw material testing
  • Product specifications
  • Assay, purity analysis
  • Trace analysis
  • Method development and validation
  • QC screening, troubleshooting
  • Identification of unknowns
  • Molecular speciation
  • More

  

Trace metal analysis laboratory techniques from Intertek ASG:

  • ICP: Inductively Coupled Plasma Spectrometry
  • ICP/OES: Optical Emission Spectrometry
  • ICP/MS: Mass Spectrometry, ICP-MS
  • AAS: Atomic Absorption Spectrometry, AA
  • Ion chromatrography

  

Trace metal analysis techniques from other Intertek laboratories:

  • GC/ICP/MS: Gas Chromatography Inductively Coupled Plasma Mass Spectrometry
  • XRF: X-Ray Fluorescence Spectrometry
  • Automated combustion techniques
  • Pyrolysis, Infra red detectors
  • Fluorescence detectors
  • Chemiluminescence detectors
  • Cold vapour atomic absorption, AAS

Trace metals detected and characterized include:

  • Toxic Materials
  • Alkali Earths, Alkali Metals
  • Transition Metals
  • Aluminium, Arsenic
  • Cadmium, Chromium, Copper
  • Gold, Iron, Lead, Lithium
  • Mercury, Nickel, Potassium
  • Precious Metals
  • Silver, Titanium, Vanadium
  • Zinc, less common analytes

  

Non-metallic compounds and molecular species tested to trace detection levels:

  • Boron, Bromine
  • Carbon, Chlorine, Chloride
  • Sulfur, Nitrogen
  • Phosphorous, Halogens, Nonmetals

  
Service Highlights include:

  • First rate method development capability across diverse product types
  • Extensive experience of method validation to ICH Guidelines for pharmaceutical products
  • Capability in trace heavy metals determination for herbal and ayurvedic medicinal products and foods
  • Elemental analysis in biological materials, including GLP studies
  • Cost effective high throughput capability for routine applications